Conclusion:
Different composition of base can affect the
physical characteristic of suppositories. High amount of PEG 6000 will produce
hard and less greasy suppository. However, high amount of PEG 1000 will give
soft and greasier suppository. Proper combination of PEG will give the optimum
drug released rate.
References:
1. Pharmaceutical Practical. (1996). Diana M. Collett,
Michael. E. Aulton.Churchill Livingstone.
2. Phsicochemical properties of
pharmacy, Florence& Attwood, 3rd Edition.
3. David Troy. 2000. Remington: The Science and Practice of Pharmacy.
Lippincott Williams & Wilkins. 21th
edition. Page 1079-1080
Appendix:
No comments:
Post a Comment